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Assessment of Bone Mineral Density (BMD) among general population of District Khuzdar, Baluchistan Pakistan
Keywords:
Bone mineral density, Menopause, Osteopenia, Osteoporosis YasinzaAbstract
Objective: To determine the frequency of osteoporosis and osteopenia among the general population of District Khuzdar, Baluchistan Pakistan.
Methods: This was a cross-sectional study and the data was collected on “World Osteoporosis Day” 20th October 2019 during an awareness session arranged by Shaheed Baz Muhammad Kakar Foundation at Baluchistan University of Information Technology, Engineering and Management Sciences Khuzdar Campus. The bone mineral density of all participants fulfilling the inclusion criteria was determined with DMS PEGASUS SMART Bone Densitometer. The T-scores were measured based on the readings of each individual and further characterized as Normal (+1 to -1 Standard Deviations), Osteopenia (-1 to -2.5 Standard Deviations), and Osteoporosis (<-2.5 SD).
Results: The total participants screened were 246 including 169(68.7%) males and 77(31.3%) females. The mean age was 37±7. Most(49.2%, n=121) participants were in the age range of 15 to 25 years. Majority (75.6%,n=186) of the participants had normal bone mineral density. Osteopenia was detected in 47(19.1%) and Osteoporosis in 13(5.3%) participants.
Conclusion: Majority of our study participants had normal bone mineral density. However, osteopenia and osteoporosis was detected in good proportion of our study sample. Proper treatment can prevent insufficiency fractures in this osteoporotic fraction of our population.
References
Cooper C, Melton LJ. Epidemiology of osteoporosis. Trends in Endocrinology & Metabolism, 1992.;3(6):224-229.
WHO.WHO scientific group on the assessment of osteoporosis at primary health care level Brussels: World Health Organization; 2004.
Karaguzel G, Holick MF. Diagnosis and treatment of osteopenia. Reviews in endocrine and metabolic disorders.2010;11(4):237-251.
Dontas I, Yiannakopoulo CS.Risk factors and prevention of osteoporosis-related fractures. J Musculoskelet Neuronal Interact.2007;7(3): 268-272.
Berlyne, GM., Ben-Ari J, Galinsky D, Hirsch M, Kushelevsky A, Shainkin R. The etiology of osteoporosis: the role of parathyroid hormone. JAMA.1974;229(14):1904-1905.
Fitzpatrick LA. Secondary causes of osteoporosis. in Mayo Clinic Proceedings. 2002. Elsevier.
Ebeling, P.R., Osteoporosis in men. New insights into aetiology, pathogenesis, prevention and management. Drugs & aging.1998;13(6):421-434.
Duggan, SN, Smyth ND, Murphy A, MacNaughton D, OKeefe SJ, Conlon KC. High prevalence of osteoporosis in patients with chronic pancreatitis: a systematic review and meta-analysis. Clinical Gastroenterology and Hepatology.2014;12(2):219-228.
Irani AD, Poorolajal J, Khalilian A, Esmailnasab N, Cheraghi Z. Prevalence of osteoporosis in Iran: A meta-analysis. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences.2013;18(9):759-765.
Al-Maatouq MA, El-Desouki MI, Othman SA. Prevalence of osteoporosis among postmenopausal females with diabetes mellitus. Saudi Medical Journal.2004;25(10):1423- 1427.
Ninkovic M, Love Sa, Tom B, Alexander GM, Compston JE, Alexander GJ. High prevalence of osteoporosis in patients with chronic liver disease prior to liver transplantation. Calcified Tissue International.2001;69(6):321-326.
Wade SW, Strader C, Fitzpatrick LA, Anthony MS,O Malley CD. Estimating prevalence of osteoporosis: examples from industrialized countries. Archives of Osteoporosis;2014. 9(1):182-186.
Habib S, Iqbal R, Shahid M, Habib A. Growing prevalence of osteoporosis in Pakistan: Call for action. J Pak Med Assoc.2015;65(2):230-1.
Vandenbroucke JP, von Elm E, Altman DG, Gotzsche PC, Mulrow CD Pocock SJ, Poole C, et al.Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration. PLoS Med.2007;4(10):297-312.
Sozen TL, Oz?s?k M, Ba?aran NC. An overview and management of osteoporosis. Eur J Rheumatol. 2017;4(1): 46-50.
Fatima M, Kassi M, Rehman R, Kasi PM, Kassi M, Afghan A K, et al. Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women. Singapore Medical Journal.2009;50(1):20-27.
Nagi D, Butt Z, Farooq F,Amar A.Frequency of osteoporosis in an ambulatory setting in Lahore using quantitative calcaneal ultrasound. J Pak Med Assoc. 2013;63:965-8.
Khokhar S, Hasan JA, Sarah Qazi S. Osteoporosis and its risk factors among menopausal women.Pak J Med Res.2014;53(2):42-5.
Sohail I, Hayat Z. Osteoporosis in healthy postmenopausal women. J Postgrad Med Inst. 2014;28(3):257-63.
Sayed SA, Khaliq A, Mahmood A. Evaluating the risk of osteoporosis through bone mass density. J Ayub Med Coll Abottabad.2016;28(4):730-3.
Durrani M, Nazli R, Qamar MA, Abubakar M, Shafiq M. Factors causing early osteoporosis in perimenopausal women.Pak J Physiol.2015;11(2):17-9.
