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Limb Salvage Surgery in Paediatric Distal Femur Osteosarcoma with Partial Cortical Resection and Coraline Silicon Bone Substitute-Case Report.
Abstract
Osteosarcoma is the most common malignant bone tumor of Paediatric and adolescent age. Historically radical treatments were opted but with advances in diagnosis and neoadjuvant chemotherapy limb salvage has now become possible in most of the cases. In this case report we presented an 8 year old girl who was diagnosed with osteosarcoma of the distal femur. She was treated successfully with neoadjvant chemotherapy followed by limb salvage surgery using partial resection of medial femoral cortex with lateral cortex remains in continuity and poraline silicon bone substitute for filling the defect. She is disease free after 3.5 year and walking pain free on her limb.
References
Segal R, Miller K, Jemal A. Cancer statistics, 2018. CA Cancer J Clin 2018;68(1):7-30.
Fletcher CD. The evolving classification of soft tissue tumours–an update based on the new 2013 WHO classification. Histopathology 2014;64(1):2-11.
Yuan G, Chen J, Wu D, Gao C. Neoadjuvant chemotherapy combined with limb salvage surgery in patients with limb osteosarcoma of Enneking stage II: a retrospective study. Onco Targets Ther 2017;10:2745-50.
Mei J, Zhu XZ, Wang ZY, Cai XS. Functional outcomes and quality of life in patients with osteosarcoma treated with amputation versus limb-salvage surgery: a systematic review and meta-analysis. Arch Orthop Trauma Surg 2014;134(11):1507-16.
Han G, Bi WZ, Xu M, Jia JP, Wang Y. Amputation Versus Limb-Salvage Surgery in Patients with Osteosarcoma: A Meta-analysis. World J Surg 2016;40(8):2016-27.
Grinberg SZ, Posta A, Weber KL, Wilson RJ. Limb Salvage and Reconstruction Options in Osteosarcoma. Adv Exp Med Biol 2020;1257:13-29.
Torner F, Segur JM, Ullot R, Soldado F, Domenech P, DeSena L,et al. Non-invasive expandable prosthesis in musculoskeletal oncology paediatric patients for the distal and proximal femur. First results. Int Orthop 2016 ;40(8):1683-1688.
Vlach M, Schovanec J, Havlas V, Wagenknecht L, Trc T. Primarni maligni nadory kosti u detí moznosti zachovne chirurgie s vyuzitim alostepu [Primary malignant bone tumors in children possibilities of limb-saving surgery using allografts]. Cas Lek Cesk 2016;155(8):406-412
Aponte-Tinao LA, Albergo JI, Ayerza MA, Muscolo DL, Ing FM, Farfalli GL. What Are the Complications of Allograft Reconstructions for Sarcoma Resection in Children Younger Than 10 Years at Long-term Followup? Clin Orthop Relat Res 2018;476(3):548-555.
Takeuchi A, Yamamoto N, Hayashi K, Matsubara H, Miwa S, Igarashi K, et al. Joint-preservation surgery for pediatric osteosarcoma of the knee joint. Cancer Metastasis Rev 2019;38(4):709-22.
Hindiskere S, Doddarangappa S, Chinder PS. What Are the Challenges and Complications of Sterilizing Autografts with Liquid Nitrogen for Malignant Bone Tumors? A Preliminary Report. Clin Orthop Relat Res 2020;478(11):2505-2519.
Ruiz-Moya A, Lagares-Borrego A, Sicilia-Castro D, Barrera-Pulido FJ, Gallo-Ayala JM, Santos-Rodas A, et al. Pediatric extremity bone sarcoma reconstruction with the vascularized fibula flap: Observational study assessing long-term functional outcomes, complications, and survival. J Plast Reconstr Aesthet Surg 2019 ;72(12):1887-1899.
Kang S, Lee JS, Park J, Park SS. Staged lengthening and reconstruction for children with a leg-length discrepancy after excision of an osteosarcoma around the knee. Bone Joint J 2017;99-B(3):401-408.
