From “Orthopaedic Surgery” to “Orthopaedic Needling.”

Authors

  • Yasir Mustafa Khan Consultant Orthopaedic & Sports surgeon YK Orthopaedics and Sports Surgery Centre Zamzamma Karachi

Keywords:

Orthopaedic Needling, Orthopaedic Surgery, platelet rich plasma, stem cells, osteoarthritis

Abstract

Knee Osteoarthritis affects millions of people around the world. Although joint replacement for end stage osteoarthritis improves the quality of life of many it is expensive and some people may not be satisfied with this procedure. However, concerns regarding conservative treatment of patients with early- to end-stage osteoarthritis is mounting. The usual conservative treatment options available for early- to moderate-stage osteoarthritis are anti-inflammatory drugs, steroids and hyaluronic acid injections, Ozone and prolotherapy. Evidence suggests that all such treatment have their own merit and demerits and none is safe in the long term. Due to potential side effects of the available treatment options, it is believed that regenerative medicine (stem cells and platelet rich plasma) can be a good alternative with better long-term outcome and minimal side effects for all stages of osteoarthritis. Regenerative medicine is the new treatment on the horizon that promises to enhances the healing process of damaged tissues and organs with or without the need of surgery and has better efficacy and safety profile.

References

Marx RE. Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg. 2004;62:489– 496.

Cook CS, Smith PA. Clinical Update: Why PRP Should Be Your First Choice for Injection Therapy in Treating Osteoarthritis of the Knee. Curr Rev Musculoskelet Med. 2018 ;11(4):583-592.

Ramaswamy Reddy SH, Reddy R, Babu NC, Ashok GN. Stem-cell therapy and platelet-rich plasma in regenerative medicines: A review on pros and cons of the technologies. J Oral Maxillofac Pathol. 2018 ;22(3):367-374.

Sanchez M, Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: A retrospective cohort study. Clin Exp Rheumatol. 2008; 26(5):910-913.

National Institute for Health and Clinical Excellence(NICE). Platelet-rich plasma injections for osteoarthritis of the knee 2019. https://www.nice.org.uk

Lysaght MJ, Crager J. Origins. Tissue Eng Part A. 2009;15:1449-1450.

Huang R, Li W, Zhao Y, Yang F, Xu M. Clinical efficacy and safety of stem cell therapy for knee osteoarthritis: A meta-analysis. Medicine (Baltimore). 2020;99(11):e19434. doi: 10.1097/MD.0000000000019434.

Prodromos C, Finkle S, Rumschlag T, Lotus J. Autologous mesenchymal stem cell treatment is consistently effective for the treatment of knee osteoarthritis: The result of a systemic review of treatment and comparison to placebo. Medicines (Basel). 2020; 7(8): 42-48.

Downloads

Published

2022-03-08

How to Cite

Yasir Mustafa Khan. (2022). From “Orthopaedic Surgery” to “Orthopaedic Needling.”. Journal of Pakistan Orthopaedic Association, 34(01), 01–02. Retrieved from http://jpoa.org.pk/index.php/upload/article/view/611