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Primary lymphoma of bone in children- A case series.
Keywords:
Chemotherapy, Diffuse Large B cell, Lymphoma, Non Hodgkin lymphoma, Primary lymphoma of boneAbstract
Lymphoma is a malignant disease primarily originating from the lymphoid cells. Lymphoma can be classified as Hodgkin (HL) and Non Hodgkin lymphoma (NHL). Most lymphoma in bones are non-Hodgkin lymphomas and 80% are Diffuse Large B cell subtype (DLBCL). All children with primary lymphoma of bone (PLB) that were diagnosed and treated at Agha Khan University Hospital from 25th October 2000 to 25th October 2020 were included in this case series. Three cases of Paediatric PLB were documented. All of them were DLBCL. Chemotherapy was started. None of them required surgery. One of them expired and the rest of the two are in remission. The disease is rare so we had very few patients. Our case series suggests that PLB in children can be managed successfully with a multidisciplinary approach and focusing on chemotherapy and radiotherapy.
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